The
clinical appearance of lesions together with a primary vaccination
site usually establishes the diagnosis. Diagnosis may be more
difficult in contact cases, because history of contact with
a vaccinee may be unknown or unappreciated as to risk.
Laboratory confirmation may be indicated in cases where distinction
from herpes virus infection or other pox diseases may be necessary.
Immunologic studies, particularly of T-cell function and IgE
levels, are recommended and should be performed in consultation
with either the CDC or an established immunologist familiar
with atopic dermatitis. In this way, the subtle immunologic
differences that contribute to the occurrence and morbidity
of this condition may be better understood.
Appropriate bacterial and/or fungal cultures of the skin or
blood may be indicated if there is evidence of contamination
or symptoms suggesting bacteremia or septicemia. If abscesses
occur, treat appropriately by incision and drainage.
|
