The
frequency of vaccinia keratitis is unknown. From the experience
of those who cared for patients with vaccinia keratitis and
from published reports, it is not a common occurrence.
There are two categories of susceptible persons:
1. Those with pre-existing eye disease
2. Those who have normal eyes
In both cases, the transfer of vaccinia virus from the hands
to the eyes can result in keratitis. Those with pre-existing
eye disease, particularly inflammatory diseases of the lids,
conjunctiva and cornea, are particularly prone to implantation
from contact with contaminated hands. Caretakers who bath
or otherwise handle children with vaccinations are the most
likely to experience such transfer.
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